Current: Catalog Peptides : Endothelin-2, Endothelin-3 & Analogs

 
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Cat# 88-5-10B
Sequence Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp
Unit
Weight 1.0  mg
MW 2643.1
CAS [117399-93-6]
Formula C121H168N26O33S4
Disulfide Bridge Disulfide bridges Cys1-Cys15, Cys3-Cys11
References            K. Nakajima et al., J. Cardiovasc. Pharmacol., 13, S8 (1989); A. Inoue, et al., PNAS, 86, 2863 (1989); M. Yanagisawa et al., PNAS, 85, 6964 (1988)

Endothelin-3, human 

 

Potent constrictor of rat blood vessels in vitro and an effective pressor agent in vivo. Endothelin-3 (ET-3) has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It displays selectivity for ETC receptor.