Current: Catalog Peptides : Corticotropin Releasing Factors

 
Product Details

Unit Price     $195.00
Your Price $195.00
Cat# 34-7-12A
Sequence DPhe-His-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
Unit
Weight 0.5  mg
MW 3650.3
CAS [220673-95-0]
Formula C161H274N48O46S
Disulfide Bridge
References            Brauns, O., et al., Secondary structure of antisauvagine analogues is important for CRF receptor antagonism: development of antagonists with increased potency and receptor selectivity. Peptides 23, 1817-27, (2002). Wang, L., et al., Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281, 1401-10, (2001). Takahashi, L.K., et al., Antagonism of CRF(2) receptors produces anxiolytic behavior in animal models of anxiety. Brain Res. 902, 135-42, (2001). Higelin, J., et al., 125I-Antisauvagine-30: a novel and specific high-affinity radioligand for the characterization of corticotropin-releasing factor type 2 receptors. Neuropharmacology 40, 114-22, (2001).

Antisauvagine-30  

 

Biochem/physiol Actions High-affinity antagonist for Corticotropin-releasing factor (CRF) receptor type 2 (CRF(2)).