Effects on feeding, energy expenditure, and obesity
NPY receptors, receptor agonists and antagonists
Effects on neuroendocrine

Effects on feeding, energy expenditure, and obesity

1. Evidence for a central mechanism of obesity in the Zucker rat: role of neuropeptide Y and leptin. BD White et al. Proceedings of the Society for Experimental Biology and Medicine 1997 Mar, 214(3):222-32.
2. The loop system between neuropeptide Y and leptin in normal and obese rodents. F Rohner-Jeanrenaud et al. Hormone and Metabolic Research, 1996 Dec, 28(12):642-8.
3. Regulation of adipose cell number in man (editorial). JB Prins et al. Clinical Science, 1997 Jan, 92(1):3-11.
4. Possible pathophysiological mechanisms regulating food intake in seasonal affective disorders. T Partonen. Medical Hypotheses. 1996 Sep, 47(3):215-6.
5. Leptin. AE Meinders et al. Netherlands Journal of Medicine, 1996 Dec, 49(6):247-52.
6. The new biology of body weight regulation. MW Schwartz et al. Journal of the American Dietetic Association, 1997 Jan, 97(1):54-8; quiz 59-60.
7. Adipogenesis and obesity: rounding out the big picture. BM Spiegelman et al. Cell, 1996 Nov 1, 87(3):377-89.
8. Role of the brain in energy balance and obesity (editorial). BE Levin et al. Am J Physiol, 1996 Sep, 271 (3 Pt2):R491-500.
9. The physiology and brain mechanisms of feeding. NE Rowland et al. Nutrition, 1996 Sep, 12(9):626-39.
10. Eating disorder research in the past decade. KA Halmi et al. Annals of the New York Academy of Sciences, 1996 Jun 18, 789:67-77.
11. Current management of obesity. JS Cheah. Singapore Medical Journal, 1996 Jun, 37(3):299-303.
12. Hormones and the ob gene product (Leptin) in the control of energy balance. P Trayhurn et al. Biochemical Society transactions, 1996 May, 24(2):565-70.
13. Metabolic actions of neuropeptide Y and their relevance to obesity. JP Wilding. Biochemical Society transactions, 1996 May, 24(2):576-81.
14. Neuropeptide abnormalities in anorexia nervosa. WH Kaye. Psychiatry Research, 1996 Apr 16, 62(1):65-74.
15. Leptin: the weight-reducing plasma protein encoded by the obese gene. Nutrition Reviews, 1996 Mar, 54(3):91-3.
16. Regulation of energy balance by leptin. A Hamann et al. Experimental and Clinical Endocrinology and Diabetes, 1996, 104(4):293-300.
17. The neural network that regulates energy balance is responsive to glucocorticoids and insulin and also regulates HPA axis responsivity at a site proximal to CRF neurons. MF Dallman et al. Annals of the New York Academy of Sciences, 1995 Dec. 29, 771:730-42.
18. New model for the regulation of energy balance and adiposity by the central nervous system. KJ Kaiyala et al. American Journal of Clinical Nutrition, 1995 Nov, 62(5 Suppl): 1123S-1134S.
19. Hypothalamic response to starvation: implications for the study of wasting disorders. MW Schwartz et al. Am J Physiol, 1995 Nov, 269(5 Pt 2):R949-57.
20. Brain peptides and obesity: Pharmacologic treatment. SF Leibowitz. Obesity Research, 1995 Nov, 3 Suppl 4:573S-589S.
21. Exercise and the neurobiological control of food intake and energy expenditure. D Richard. International Journal of Obesity and Related Metabolic Disorders, 1995 Oct,19 Suppl 4:S73-9.
22. Neural control of feeding. I Kupfermann. Current Opinion in Neurobiology, 1994 Dec, 4(6):869-76.
23. Arenal steroid receptors: interactions with brain neuropeptide systems in relation to nutrient intake and metabolism. DL Tempel et al. Journal of Neuroendocrinology, 1994 Oct, 6(5):479-501.
24. Role of neuropeptides in the regulation of feeding behavior: a review of cholecyctokinin, bombesin, neuropeptide Y, and galanin. MC Lee et al. Neuroscience and biobehavioral reviews, 1994 Fall, 18(3):313-23.
25. Neuropeptide Y and energy balance: one way ahead for the treatment of obesity? S Dryden et al. European Journal of Clinical Investigation, 1994 May, 24(5):293-308.
26. Neuropeptide Y: a central regulator of energy homeostasis. JD White. Regulatory peptides, 1993 Dec 10, 49(2):93-107.
27. Neurotransmitters and food intake (editorial). WT Chance et al. Nutrition, 1993 Sep-Oct, 9(5):470-1.
28. Insulin, neuropeptide Y, and food intake. MW Schwatz et al. Annals of the New York Academy of Sciences, 1993 Aug 27, 692:60-71.
29. The nutrient balance hypothesis: Peptides sympathetic activity, and food intake. GA Bray. Annals of the New York Academy of Sciences, 1993 Mar 15, 676:223.
30. Comparative aspects of the role of neuropeptide Y in the regulation of the vertebrate heart. H Xiang. Cardioscience, 1994 Dec, 5(4):209-13.

NPY receptors, receptor agonists and antagonists

1. Structural diversity of receptors for neuropeptide Y, peptide YY and pancreatic polypeptide. D. Larhammar. Regulatory Peptides, 1996 Sep 16, 65(3):165-74.
2. Recent developments with neuropeptide Y receptor antagonists. JM Lundberg et al. Trends in Pharmacological Sciences, 1996 Sep, 17(9):301-4.
3. BIBP 3226, the first selective neuropeptide Y1 receptor antagonist: a review of its pharmacological properties. HN Doods et al. Regulatory Peptides, 1996 Aug 27, 65(1):71-7.
4. Apparent affinity and potency of BIBP3226, a non-peptide neuropeptide Y receptor antagonist, on purported neuropeptide Y Y1, Y2 and Y3 receptors. D Jacques et al. European Journal of Pharmacology, 1995 May 4, 278(1):R3-5.
5. Neuropeptide Y receptor subtypes. CP Wan et al. Life Sciences, 1995 Feb 17, 56(13):1055-64.
6. Structure-activity relationships of neuropeptide Y analogues with respect to Y1 and Y2 receptors. AG Beck-sickinger et al. Biopolymers, 1995, 37(2):123-42.
7. Neuropeptide Y in sympathetic co-transmission: recent advances in the search for neuropeptide Y antagonsits. L Edvinsson et al. Pharmacology and Toxicology, 1994 Apr-May, 74(4-5):193-201.
8. High-affinity analogues of neuropeptide Y containing comformationally restricted non-proteinogenic amino acids. AG Beck-Sikinger et al. Biochemical Society Transactions, 1994 Feb, 22(1):145-9.
9. Subtypes of receptors for neuropeptide Y: implication for the targeting of therapeutics. DR Gehlert. Life Sciences. 1994, 55(8):551-62.
10. Multiple neuropeptide Y receptors are involved in cardiovascular regulation. Peripheral and central mechanisms. L Grundemar et al. General Pharmacology, 1993 Jul, 24(4):785-96.
11. Cardiovascular effects of neuropeptide Y: receptor interactions and cellular mechanisms. BJ McDermott et al. Cardiovascular Research, 1993 Jun, 27(6):893-905.
12. Neuropeptide Y-related peptides and their receptorsinteractions and cellular mechanisms. BJ McDermott et al. Cardiovascular Research, 1993 Jun, 27(6):893-905.

Effects on neuroendocrine

1. Nutritional infertility: the role of the interconnected hypothalamic neuropeptide Y-galanin. BJ McDermott et al. Cardiovascular Research, 1993 Jun, 27(6):893-905.
2. Role of NPY neurons in GH-dependent feedback signalling to the brain. YY Chen et al. Hormone Research, 1996, 45 Suppl 1:12-4.
3. The neural network that regulates energy balance is responsive to glucocorticoids and insulin and also regulates HPA axis responsivity at a site proximal to CRF neurons. MF Dallman et al. Annals of the New York Academy of Sciences, 1995 Dec.29, 771:730-42.
4. Hypothalamic response to starvation: implications for the study of wasting disorders. MW Schwartz et al. Am J Physiol, 1995 Nov, 269(5 Pt 2):R949-57.
5. Central insulin may up-regulate thyroid activity by suppressing Neuropeptide Y release in the paraventricular nucleus. MF McCarty. Medical Hypotheses, 1995 Aug, 45(2):192-9.
6. Neuropeptide Y, the hypothalamus, and diabetes: insights into the central control of metabolism. HM Frankish et al. Peptides, 1995, 16(4):757-71.
7. Corticotropin-releasing factor and neuropeptide Y: role in emotional integration. Trends in Neurosciences, 1994 Feb, 17(2):80-5.
8. Involvement of neuropeptides in the regulation of growth, structure and function of the adrenal cortex. LK Malendowicz. Histology and Histopathology, 1993 Jan, 8(1):173-86.
9. Visceroendocrine responses elicited by neuropeptide Y in the nucleus tractus solitarius. E Ergene et al. Brain Research Bulletin, 1993, 32(5):461-5.

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