Our customers are continually developing innovative therapies to treat a multitude of chronic illnesses. Particularly in the area of cardiovascular ailments, peptide-based therapies have seen considerable success with a number of promising indications. We recently partnered with Capstone Therapeutics to help the company develop novel therapies based on Capstone's thrombin peptide, Chrysalin (TP508 or rusalatide acetate). It is a novel synthetic 23-amino acid peptide that has been proven in multiple pre-clinical and clinical models to minimize cardiovascular tissue damage by initiating a series of anti-apoptotic events.
Drugs based on the Chrysalin peptide can be used to mimic the tissue repair aspect of thrombin activity without stimulating the events associated with blood clotting. Therefore, it has the potential to accelerate the natural cascade of healing events in a wide range of tissue injuries. Based on this ability, initial development efforts with Chrysalin were focused on speeding the healing process for bone fractures.
The eventual goal for Capstone is to develop Chrysalin into a therapy that limits the damage to heart muscle caused by a heart attack, increasing the chance of surviving the initial attack as well as protecting cardiac function over time. If successful, this approach will represent a significant clinical advance in the treatment of this life-threatening condition.
American Peptide is the number one company for providing peptides. American Peptide has supplied our company peptide reagents for over ten years and we have been very happy with their service and product. From a few milligrams to gram amounts they produce high quality product in a quick response. Furthermore, American Peptide has performed several tough synthesis's that other companies have refused to attempt and these synthesis's have turned out fantastic. In addition to producing quality product, American Peptide has a great customer service department. If you have any questions about a synthesis, product or general peptide question they are readily available to answer your questions and concerns. I would, without any hesitation, recommend American Peptide as your number one peptide supplier.
- Principal Scientist,
Biochemistry and Enzymology in Research and Development
APC has always provided me with the utmost customer service by maintaining excellent communication regarding project progress. In addition, whether ordering milligram or gram size quantities, I am confident I will receive high quality materials at competitive prices. Because of this, my group always considers APC when ordering peptides
- Associate Director,
Back to [ Peptide Wire vol.1 no.1 ]
[ President's Letter ] [ Personnel Update ] [ Technology Update
] [ Ask the Expert ] [ Test your Peptide IQ ]