# 5-Amino-1MQ

> Small-molecule NNMT inhibitor (often catalogued alongside peptides).

- Class: Metabolic, Longevity
- FDA approved: No
- Canonical page: https://www.americanpeptide.com/catalog/5-amino-1mq

## Overview

5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT). Preclinical work links NNMT inhibition to improvements in adipose tissue metabolism and skeletal muscle aging.

5-Amino-1MQ is a small molecule — not a peptide — that is frequently catalogued alongside research peptides because of its metabolic focus. It selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT).

NNMT consumes methyl groups and influences cellular NAD+ and SAM pools; inhibiting it is studied in preclinical work for improved adipose-tissue metabolism and muscle aging. It is a research compound and is not FDA-approved.

## Mechanism

NNMT inhibition → preserved cellular NAD+ / SAM pools.

## Chemistry

| Property | Value |
| --- | --- |
| Molecular formula | C10H11N2+ |
| Molecular weight | 159.21 Da |
| CAS number | 209783-80-2 |
| PubChem CID | [950107](https://pubchem.ncbi.nlm.nih.gov/compound/950107) |

## Research areas

Studied in: Obesity, Sarcopenia, NAD+ biology.

Guides on this site:

- [Weight Loss & Metabolic Health](https://www.americanpeptide.com/research-areas/weight-loss): Incretin and metabolic peptides studied for glycemic control and fat loss.
- [Longevity & Aging](https://www.americanpeptide.com/research-areas/longevity-aging): Peptides studied across the aging axis — senescence, NAD+, and resilience.

## Key research

- NNMT inhibition — selectively blocks nicotinamide N-methyltransferase.
- Adipose metabolism — studied for effects on fat-tissue energy handling.
- Sarcopenia — examined for skeletal-muscle aging.
- NAD+ / SAM pools — NNMT inhibition linked to preserved methyl-donor and NAD+ metabolism.
- Small molecule — not a peptide; not FDA-approved.

## FAQs

### What is 5-Amino-1MQ?

5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT, studied in metabolic and aging research; it is catalogued here alongside peptides for its metabolic relevance.

### Is it a peptide?

No — it is a small molecule, not a peptide, but it is grouped with metabolic research compounds.

### What is it studied for?

Obesity, sarcopenia (muscle aging), and NAD+ biology, primarily in preclinical models.

### Is it approved?

No — it is a research compound. This page is a research and educational reference.

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Source: AmericanPeptide.com — https://www.americanpeptide.com/catalog/5-amino-1mq
Data license: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Attribution: AmericanPeptide.com.
Research reference only — computational and educational content, not medical advice.