Cognitive

Semax

Russian synthetic ACTH(4-10) analog studied for nootropic and neuroprotective effects.

Overview

Semax is a heptapeptide analog of ACTH(4-10) developed in Russia, used clinically there for stroke and cognitive disorders. Preclinical studies report BDNF / NGF upregulation.

Mechanism

BDNF / NGF induction; melanocortin signaling without HPA activation.

Research areas

Ischemic stroke recovery
Cognition
Neuroprotection

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