Also called dose response · exposure-response
The dose-response relationship describes how the magnitude (and sometimes character) of a biological effect changes with increasing dose. A monotonic positive relationship — more dose, more effect — is expected for most agonists. Plateau (maximum effect) and U-shaped curves (high dose less effective than low dose) are also observed. Establishing dose-response is a primary goal of Phase 2 trials.
Research use only. This definition is an educational reference, not medical advice or dosing guidance.