MetabolicLongevity

5-Amino-1MQ

Small-molecule NNMT inhibitor (often catalogued alongside peptides).

Overview

5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT). Preclinical work links NNMT inhibition to improvements in adipose tissue metabolism and skeletal muscle aging.

Mechanism

NNMT inhibition → preserved cellular NAD+ / SAM pools.

Research areas

Obesity
Sarcopenia
NAD+ biology

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