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Melanotan II

Also known as MT-2 · MT-II

Synthetic cyclic analog of α-MSH; non-selective melanocortin receptor agonist.

Overview

Melanotan II is a cyclic heptapeptide α-MSH analog developed at the University of Arizona. Acts as a non-selective agonist across MC1R, MC3R, MC4R, and MC5R — pigmentation and sexual-response effects have both been documented.

Mechanism

Non-selective melanocortin receptor (MC1-5R) agonism.

Research areas

  • Pigmentation biology
  • Sexual dysfunction
  • Photoprotection

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