/Catalog/SS-31
MitochondrialLongevity

SS-31

Also known as Elamipretide · Bendavia

Mitochondria-targeted cardiolipin-binding tetrapeptide.

Overview

SS-31 (elamipretide) is a synthetic tetrapeptide that concentrates in the inner mitochondrial membrane and binds cardiolipin, stabilizing electron transport chain organization in clinical trials for primary mitochondrial myopathy and Barth syndrome.

Mechanism

Cardiolipin binding; preservation of cristae architecture and ETC efficiency.

Research areas

  • Mitochondrial myopathy
  • Barth syndrome
  • Heart failure

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