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Glossary/Disulfide Bond
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Peptide Chemistry

Disulfide Bond

Also called disulfide bridge · cystine bridge

A disulfide bond is a covalent linkage between the sulfur atoms of two cysteine residues. These bonds stabilize the three-dimensional structure of many peptides and proteins, and their formation is a common consideration in synthesis.

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Research use only. This definition is an educational reference, not medical advice or dosing guidance.