Also called GcgR · glucagon receptor
Glucagon is a hormone secreted by pancreatic alpha cells that raises blood glucose by promoting glycogenolysis and gluconeogenesis. It is the physiological counter to insulin. Retatrutide is a triple agonist at GLP-1, GIP, and glucagon receptors, with the glucagon component proposed to drive additional fat mobilization beyond what dual agonists achieve.
Research use only. This definition is an educational reference, not medical advice or dosing guidance.