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Glossary/Pulsatile Release
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Mechanisms & Biology

Pulsatile Release

Also called GH pulse · pulsatility

Pulsatile release describes hormones secreted in discrete pulses rather than continuously. GH is released in bursts — primarily at night — driven by alternating GHRH and somatostatin signals. GHRH analogs and GHRPs amplify pulse amplitude while preserving this pattern, which is considered more physiological than continuous exogenous GH administration.

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Research use only. This definition is an educational reference, not medical advice or dosing guidance.