AmericanPeptide
Research areas/Wound Healing & Tissue Repair
Research area · 6 peptides

Wound Healing & Tissue Repair

Regenerative peptides studied for soft-tissue, tendon, and vascular repair.

Overview

Tissue-repair peptides are studied for their effects on angiogenesis, fibroblast and keratinocyte activity, and the cytoprotective signaling that governs how injured tissue recovers. The interest spans dermal wounds, tendon and ligament injury, cartilage, and ischemic or post-surgical repair models.

Mechanisms under investigation include up-regulation of growth-factor receptor expression, modulation of the nitric-oxide system, actin sequestration and cell migration, and copper-dependent remodeling of the extracellular matrix. Most evidence here is preclinical, making rigorous model selection and endpoint definition especially important.

Peptides studied in wound healing & tissue repair